The Tortosa Jewish quarter is well signposted and by following the signs, visitors can easily find the site of the synagogue, the early Talmudic school, the pottery, where Jewish hands carried on the Muslim tradition, or the bakery, where unleavened bread was baked for the Hebrew community.

The anti-Jewish revolts of 1391 were not as violent in Tortosa as elsewhere in Sepharad. Even so, to ensure their safety, the local authorities decided to confine the Hebrew community to the Castle of La Suda (now a Parador hotel), which stood on the city acropolis. The Tortosa Disputation, however, was famous throughout Spain and Europe. It was organized by Pope Benedict XIII, but initiated by his physician, a converso called Jerónimo de Santa Fe. Tortosa cathedral was the backdrop for almost sixty public meetings, which lasted until 1414, and were chaired by the Pope. They were attended by the wisest of Jewish scholars, who debated the issue of the coming of the Messiah, which was the main point of controversy between Jews and Christians. The outcome was that all those Jews who took part in the polemic, except two, converted. It was a foretaste of what was to come with the Papal Bull of 1415, which seriously restricted the freedom of Jews.